The human gut is more densely populated with microorganisms than anywhere else on the planet. It is estimated that around a thousand different species of microorganisms living in the human gut, and they form a complex microorganism population called the "microbiota". The composition of the gut microbiota varies by dietary and lifestyle habits, among other factors, and therefore differs between individuals.
The gut microbiota not only live in the human gut, but also play large roles in maintaining human health. One of the most fundamental roles of the gut microbiota is in digestion; the gut microbiota strongly influence how ingested food or medicine is digested, absorbed and stimulates gastrointestinal cells. On the other hand, the substances produced by digestion, known as metabolites, also affect the composition and functions of the microbiota. Therefore, to evaluate the intestinal environment, it is important to understand both the composition of the gut microbiota and the availability of metabolites.
To this end, we established "Metabologenomics®", an integrative study of microbiota by "Metagenomics" and of metabolites by "Metabolomics".